Symptoms reported by elderly patients with isolated systolic hypertension: baseline data from the SYST-EUR trial. Systolic Hypertension in Europe
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منابع مشابه
Symptoms reported by elderly patients with isolated systolic hypertension: baseline data from the SYST-EUR trial. Systolic Hypertension in Europe.
OBJECTIVES To determine the symptomatic well-being of elderly persons with isolated systolic hypertension. DESIGN AND SETTING Well-being determined during the placebo run-in period prior to entry to the Systolic Hypertension in Europe (SYST-EUR) trial. SUBJECTS 641 People, 60 years or older with an average sitting blood pressure of 173/86 mm Hg. OUTCOME MEASURES 33 Symptomatic complaints ...
متن کاملUpdate on the systolic hypertension in Europe (Syst-Eur) trial. The Syst-Eur Investigators.
The Syst-Eur trial was stopped after the second of 4 planned interim analyses, when predefined stopping rules1 revealed that active treatment diminished the incidence of stroke, the primary endpoint. The ethics committee unanimously resolved that all endpoints that had occurred before February 14, 1997, at 5 PM should be included in the final analysis. The long communication lines between the c...
متن کاملQuality of life on randomized treatment for isolated systolic hypertension: results from the Syst-Eur Trial.
OBJECTIVE To compare quality of life in elderly patients with isolated systolic hypertension allocated randomly to groups to receive placebo or active treatment in the Systolic Hypertension in the Elderly Trial. DESIGN Double-blind randomized controlled trial. METHODS Patients aged 60 years were allocated randomly to groups to receive first-line treatment with nitrendipine (with second- and...
متن کاملRandomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators.
BACKGROUND Isolated systolic hypertension occurs in about 15% of people aged 60 years or older. In 1989, the European Working Party on High Blood Pressure in the Elderly investigated whether active treatment could reduce cardiovascular complications of isolated systolic hypertension. Fatal and non-fatal stroke combined was the primary endpoint. METHODS All patients (> 60 years) were initially...
متن کاملChinese trial on isolated systolic hypertension in the elderly. Systolic Hypertension in China (Syst-China) Collaborative Group.
BACKGROUND In 1988, the Systolic Hypertension in China (Syst-China) Collaborative Group initiated the placebo-controlled Syst-China trial to investigate whether antihypertensive drug treatment could reduce the incidence of fatal and nonfatal stroke in older Chinese patients with isolated systolic hypertension. OBJECTIVES To explore (1) whether the benefits of active treatment were evenly dist...
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ژورنال
عنوان ژورنال: Age and Ageing
سال: 1999
ISSN: 1468-2834
DOI: 10.1093/ageing/28.1.15